BARCELONA SCIENCE WEEK

Barcelona, global science and health 'hub': challenges and opportunities

06 april of 2025 at 22:34h

Barcelona has consolidated itself in recent decades as one of Europe's most dynamic and vibrant science and health hubs. With a network of reference hospitals, cutting-edge research centers, and a powerful business community with a global mindset, the city has become an ecosystem capable of generating high-impact innovation.

But, at what point is the sector really? What is the role of hospitals like Sant Joan de Déu in this context?

Infrastructures and expansion: a necessary leap

The Catalan capital has made a significant effort to boost its scientific and healthcare infrastructures. Projects such as the expansion of the Hospital Sant Joan de Déu Barcelona with the Unicas building, financed by philanthropy; the consolidation of the Barcelona Supercomputing Center (BSC), a major commitment of European, Spanish, and Catalan scientific policy to frontier computing; the presence of biomedical faculties and the Barcelona Science Park of the University of Barcelona (PCB), or the expansion of Hospital Clínic to a new location less than 500 linear meters from the previous centers, will allow Barcelona to be at the forefront of global biomedical research.

However, this expansion entails significant challenges. Adapting to new technologies, attracting and retaining talent, and the need to make infrastructures more sustainable and efficient are key factors to guarantee the growth of this ecosystem.

If we look at the major challenges facing Hospital Sant Joan de Déu in the coming years, all are linked to personalized and precision medicine, the vanguard of that desired future. The care capacity, clinical experience, patient volume, and the firm purpose of wanting to be at the frontier of knowledge in the field of rare diseases are a hallmark of this hospital. The goal is to provide solutions for vulnerable and often forgotten populations, where the interests of industry and even public research often pass by.

Rare diseases: a global challenge

Minority diseases, also known as rare diseases, are those that affect fewer than 1 in 2,000 people. Despite their low individual prevalence, it is estimated that, as a whole, there are between 6,000 and 8,000, and they impact the lives of more than 300 million people worldwide, 30 million in Europe, and three million in Spain. These pathologies present significant challenges in terms of diagnosis, treatment, and data management, but they also open up opportunities thanks to technological and scientific advances.

Simulated image of the interior of the future Unicas center in Sant Joan de Déu.

Faster and more accurate diagnosis: the genomic revolution and AI

Diagnosing a minority disease can be a long and frustrating process. It is estimated that the average time to identify one of these pathologies is about four years, and only half of the cases achieve an accurate diagnosis. Often, the absence of a reliable diagnosis results in inadequate or ineffective treatments, which affects both patients and their families, who live in a situation of great vulnerability.

The great challenge is to offer effective treatments for diseases that, until recently, lacked any therapeutic option
The key to reducing this time lies in the incorporation of genomic sequencing, multiomic techniques, and the intensive use of artificial intelligence (AI). The Sant Joan de Déu Hospital has firmly committed to these technologies and, thanks to the analysis of genetic data and collaboration with international networks, has managed to diagnose extremely complex cases.

New therapies: the promise of personalized medicine

Diagnosis is only the first step. The great challenge is to offer effective treatments for diseases that, until recently, lacked any therapeutic option. In this field, Sant Joan de Déu has become a benchmark in the development of gene and cell therapies.

The power of data: a revolution in biomedical research

In an increasingly interconnected world, the ability to analyze large volumes of clinical and genomic data is a determining factor in medical research. Sant Joan de Déu has opted for health big data platforms that allow cross-referencing information from thousands of patients to identify patterns and trends that could lead to new discoveries.

One of the operating rooms at Sant Joan de Déu Hospital.

Future challenges: towards a more competitive Barcelona

Despite its success, Barcelona's science and health sector still faces important challenges. The need for better public-private collaboration, improved technology transfer to the market, and the integration of artificial intelligence into medical and scientific processes are some of the imminent challenges. However, the most important challenge is for Barcelona to know how to compete to attract the best human talent, the most limited resource, in a highly competitive market.

Furthermore, we must not forget that we do everything with and for patients and their families. This is a strategy to which the Sant Joan de Déu Hospital feels fully committed, placing patients at the center of all activity, including research and innovation.